PECS research and activities are guided by the PECS Scientific Committee (PECS-SC), which is appointed jointly by the International Council for Science (ICSU) and the United Nations Educational, Scientific and Cultural Organization (UNESCO).

The PECS-SC consists of a Chair and 12 additional members that are appointed for a period of three years, renewable once. In addition to this, each sponsor, and the Scientific Committee for DIVERSITAS, have representatives serving as ex-officio members.

PECS activities are supported by the PECS International Programme Office (PECS-IPO). The PECS-IPO is in charge of implementing the vision and recommendations of the PECS-SC. The IPO is responsible for engaging the international community, establishing networks and coordinating activities. It also communicates the results of PECS activities through reports, the PECS website and publications.